Abstract:

Objectives: The aim of this study was to determine ef­fect of N-Butyl-2 Cyanoacrylate (CA) and lipiodol mixture injection for hemostasis of bleeding gastric varices or le­sions, which had bled from gastric varices. Materials and methods Fifteen patients with active bleeding or bleeding findings within two weeks who ad­mitted to endoscopic unit of a low volume medical center were evaluated retrospectively between 2003 and 2010. We carried out endoscopic sclerotherapy successfully to gastric varices with combination of N-Butyl-2 Cyanoacry­late and Lipiodol (CALM), with dramatical success over months after sessions of sclerotherapy for each patient. Results: Sclerotherapy with cyanoacrylate achieved hemostasis in all actively bleeding nine patients initially. Rebleeding occurred in a patient 24 hours later and in another patient two months later (2/15, 13.3%). Eradica­tion of gastric varices was achived in 13 (86.7 %) patients during follow-up. One patient was operated because of rebleeding. One patient died as a result of liver failure. Five-year survival rate of the patients after eradication of gastric varices was 14/15 (93.3%). Conclution: This study indicated that sclerotherapy with N-Butyl-2 Cyanoacrylate and lipiodol mixture is an effec­tive treatment method for patients with bleeding gastric varices and also for eradication of gastric varices.

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