Özet:

Coronaviridae (CoVs) in the family can cause gastrointestinal, respiratory and systemic diseases in wild and domestic animals with different severities, while in humans it can lead to different clinical tables, from colds to pneumonia, depending on the immune condition. So far, seven types of coronavirus have been identified as an infection factor in humans, including HCoV 229E, HCoV NL63, HCoV HKU1 and HCoV OC43, typically causing cold symptoms in immune-competent individuals, while SARS-CoV (Serious Acute Respiratory Syndrome Coronavirus), MERS-CoV (Middle East Respiratory Syndrome Coronavirus) are zoonotic and cause severe respiratory diseases and deaths. China's Hubei state, Wuhan, was the seventh coronavirus that was identified as an infection agent in humans, the SARS-CoV-2 factor of COVID-19 which began in December 2019 and was soon defined as a pandemic. As the World Health Organization (WHO) has defined SARS-CoV-2-based COVID-19 as a pandemic and the world’s daily increase in cases and deaths has become even more important to the use of viral diagnosis methods, which are the critical stage in controlling the virus’s structure and epidemic for vaccination studies.

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