Abstract:

Background: Several biochemical tests are useful in the evaluation and management of patients with hepatic dysfunction.These tests can be used to detect the presence of liver disease, distinguish among different types of liver disorders, gauge the extent of known liver damage, and follow the response to treatment.ALT reflects damage to hepatocytes and it is found primarily in liver in low concentrations and get released into the blood in greater amount when there is damage to liver cell membrane resulting in increased permeability.The activity of ALP in a pathological condition is usually elevated in cholestasis.Non-pathologically it is also elevated in children and adolescents undergoing rapid bone growth and in late pregnancy.The main objective of this study was to correlate these serum biomarkers with the histopathological reports of the resected gallbladder specimen.

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