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Amaç: Bu çalışmada amacımız, Gerçek Zamanlı Polimeraz Zincir Reaksiyonu (RT-PCR) pozitif olup bilgisayarlı tomografi (BT) -pozitif COVID-19 hastalarının ve BT-negatif COVID-19 hastalarının C-reaktif protein/Albümin oranı (CAO) değerlerini tespit etmek ve RT-PCR pozitif hastalarının C-reaktif protein/Albümin oranı ile radyolojik görüntüleri arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntemler: Çalışmamıza 18 yaş üstü 100 RT-PCR pozitif COVID-19’lu hasta dahil edildi. C-reaktif protein (CRP), albümin seviyeleri, diğer veriler ve akciğer BT taraması toplandı. Hastalar iki bölüme ayrıldı: BT-pozitif ve BT-negatif. Komorbidite dışlanmadan ve dışlanarak CAO ve BT taraması arasındaki ilişkiyi araştırdık. Bulgular: BT pozitif grupta ölçülen CRP seviyeleri ve CAO değerleri, BT negatif gruba göre anlamlı olarak yüksekti (CRP:37.76 ± 64, 9.05 ± 22, p <0.05, CAO:11.8 ± 23.2, 2.12 ± 5.42, p <0.05). Ölçülen albümin seviyeleri BT-pozitif grubu, BT negatif gruba göre anlamlı derecede düşüktü (4.12±0.63, 4.53±0.36, p <0.05). Komorbiditesi olmayan hastaları değerlendirdiğimizde; BT-pozitif grupta ölçülen CRP seviyeleri ve CAO, BT-negatif gruba göre anlamlı olarak yüksekti (15.94 ± 19.2, 6.07 ± 7.38, p <0.05, 4.57 ± 6.82, 1.38 ± 1.75, p <0.05). BT-pozitif hastaların albümin değerleri BT-negatif hastalarınkinden daha düşük olmasına rağmen, istatistiksel olarak anlamlı bulunmamıştır. Sonuç: Genel olarak CAO düzeylerini BT-pozitif hastalarda, BT-negatif hastalara göre anlamlı olarak yüksek bulduk. Ancak komorbiditeyi dışladığımızda C-reaktif protein/albümin oranının azaldığını da göz önünde bulundurmak gerekir. BT'nin kontrendike olduğu durumlarda (gebelik gibi) akciğer tutulumunu göstermek veya akciğer tutulumu olan hastalarda parankimal tutulumda olası artışı göstermek için öncü bir belirteç olarak kullanılabileceği düşünülebilir.
Purpose: In this study, our goal is to identify the values of Real-Time Polymerase Chain Reaction (RT-PCR) positive and computer tomography (BT) positive COVID-19 patients and BT-negative COVID-19 patients C-reactive protein/albumine ratio (CAO) and to explore the relationship between the RT-PCR positive patients C-reactive protein/albumine ratio and radiological images. Tools and Methods: 100 RT-PCR positive COVID-19 patients over the age of 18 were included in our study. C-reactive protein (CRP), albumin levels, other data and lungs BT scan were collected. Patients were divided into two divisions: BT-positive and BT-negative. We studied the relationship between CAO and IT scan by excluding and excluding comorbidity. Results: CRP levels and CAO values measured in the BT positive group were significantly higher compared to the BT negative group (CRP:37.76 ± 64, 9.05 ± 22, p <0.05, CAO:11.8 ± 23.2, 2.12 ± 5.42, p <0.05). The levels of the album measured were significantly lower compared to the BT-positive group, the BT negative group (4.12±0.63, 4.53±0.36, p <0.05). When we assessed patients with non-comorbidity, the levels of CRP and CAO measured in the BT-positive group were significantly higher compared to the BT-negative group (15.94 ± 19.2, 6.07 ± 7.38, p <0.05, 4.57 ± 6.82, 1.38 ± 1.75, p <0.05). Although the album values in BT-positive patients were lower than in BT-negative patients, it was not statistically meaningful. The result: In general, CAO levels were significantly higher in BT-positive patients, compared to BT-negative patients. But when we exclude comorbidity, it is also necessary to take into account that the C-reactive protein/albumin ratio is reduced. It may be considered to be used as a leading indicator in cases where BT is contraindicate (such as pregnancy) to show a lungs attitude or to show a possible increase in parankimal attitude in patients with lungs attitude.
Aim: Our aim in this study is to determine the C-reactive protein/Albumin ratio (CAR) values of computed tomography (CT) -positive COVID-19 patients and CT-negative COVID-19 patients who are Real-Time Polymerase Chain Reaction (RT-PCR) and to investigate the relationship between C-reactive protein / Albumin ratio and radiological images of RT-PCR positive patients. Material and Methods: 100 RT-PCR positive COVID-19 patients over the age of 18 were included in our study. C-reactive protein (CRP), albumin levels, other data and lung CT scan were collected. The patients were divided into two sections: CT-positive and CT-negative. The relationship between CT and CAR was investigated in patients with and excluding comorbidity. Results: The measured CRP levels and CAR in the CT-positive group were significantly higher than CT-negative group (37.76±64, 9.05±22, p <0.05, 11.8±23.2, 2.12±5.42, p <0.05). The measured albumin levels CT-positive group were significantly lower than CT-negative group (4.12±0.63, 4.53±0.36, p <0.05). When we evaluate patients without comorbidity the measured CRP levels and CAR in the CT-positive group were significantly higher than CT-negative group (15.94±19.2, 6.07±7.38, p <0.05, 4.57±6.82, 1.38±1.75, p <0.05). Although the albumin values of CT-positive patients were lower than those of CT-negative patients, no statistically significance was found. Conclusion: In general, we found that CAR levels in CT-positive patients were significantly higher than in CT-negative patients. However, when we exclude the comorbidity, it should be taken into account that the ratio of C-reactive protein/albumin decreases. It can be considered that CT can be used as a leading marker to show lung involvement in cases where it is contraindicated (such as pregnancy) or to show possible increase in parenchymal involvement in patients with lung involvement.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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