Özet:

To ensure the proper management of laboratory spinal pain is the task and responsibility of scientists working with these types. This collection aims to raise awareness of the pain they hear in the experiments of laboratory kidneys serving scientists. The anatomical structures and neurophysical mechanisms that cause the perception of pain in humans are in similar structure in animals. Therefore, when pain occurs in scientific experiments, as well as in humans, evacuation, stress, pain and endocrine and physiological changes occur in animals. First of all, if the treatment is associated with the expected pain, an analgesic plan should be made before the procedure is implemented. It may not be enough to relieve the pain after the pain is felt and physiological changes occur. This may require pre-analysis. It should be preferred to use the multimodal analgesic method. Formal, standard and sufficient pain monitoring and treatment practices can be easily in publications and can contribute to better transparency and repetitiveness of the experiment. Thus, the increase in scientific quality prevents the unnecessary suffering of animals. Pain management should be planned in advance in laboratory animal studies, implemented and continued after scientific research. It is known that the selection of analgesic and anesthetic substances has significant effects on both animal well-being and the results of the study. The doses and methods indicated in the guidelines should be carefully selected and applied according to the animal model that is studied. The guidelines should also be checked from the point of view of pain, often re-configured, updated. Keywords: analgesia, pain, pain

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