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Vajinismuslu İnfertil Kadınların Yardımcı Üreme Teknikleriyle Yönetimi
2021
Journal:  
Journal of Academic Research in Medicine
Author:  
Abstract:

Amaç: Şiddetli vajinismus tanısı almış infertil olguların in vitro fertilizasyon ve embriyo transferi (IVF-ET) sonuçlarını sağlıklı infertil kontrollerle karşılaştırmaktır. Yöntemler: Vajinismusa bağlı kısırlık şikayeti ile başvuran hastalar arasından 29 hasta seçildi. Vajinismus tanısı ve şiddeti Lamont-Pacik sistemine göre konuldu. Hafif vajinismus formlarına sahip 5 kadın başka yöntemlerle tedavi edildi. Çalışmaya dahil edilen ve şiddetli vajinismus tanısı alan toplam 24 olgunun 20 tanesi Lamont grade 3 ve geriye kalan 4 olgu ise Lamont grade 4 idi. Açıklanamayan infertilite tanısı alan 24 hasta kontrol grubu olarak seçildi. Bulgular: Yirmi dört hastanın 15’i ilk IVF-ET denemesinde, 8 hasta ikinci ve bir hasta da 4. denemesinde idi. Vücut kitle indeksi (VKİ) normal olan 21 vajinismuslu kadına abdominal ultrasonografi ile folikülometri yapıldı. VKİ yüksek olan 3 olguda ise sedasyon altında transvajinal ultrasonografi ile hem folikülometri hem de endometriyal değerlendirme yapıldı. Yirmi yedi siklusta tek ET, 8 siklusta ise iki ET gerçekleştirildi. Otuz dokuz siklusun 20’sinde beta human karyonik gonodotropin pozitifliği tespit edildi. Benzer şekilde 20 olguda klinik gebelik tespit edilirken (%51,2) term ve canlı doğum ile sonuçlanan siklus sayısı 16 idi (%41). Kontrol grubundaki olgularda 35 siklusun 25’inde klinik gebelik oranı (CPR) saptanırken (%71,4) 22 siklusta canlı doğum oranı (CDO) sağlandı (%62,8). Vajinismus grubu ile karşılaştırıldığı zaman CPR (20 vs 25, p<0,09) ve LBR oranları benzer olarak bulundu (16 vs 22, p<0,06). Sonuç: IVF-ET uygulanan şiddetli vajinismuslu infertil kadınların hem klinik gebelik hem de CDO’ları, açıklanamayan infertiliteye sahip kadınlarla benzerdir.

Keywords:

Management of Vaginism Infertile Women with Assistant Reproductive Techniques
2021
Author:  
Abstract:

The purpose is to compare the results of in vitro fertilization and embryo transfer (IVF-ET) of infertile events diagnosed with severe vaginism with healthy infertile controls. Methods: 29 patients were selected among the applicants with the Vaginism-related infertility complaint. The diagnosis and severity of vaginism was placed according to the Lamont-Pacik system. Five women with mild vaginism forms were treated by other methods. In total, 20 of the 24 phenomena involved in the study and diagnosed with severe vaginism were Lamont grade 3 and the remaining 4 phenomena were Lamont grade 4. 24 patients diagnosed with unexplicable infertility were selected as a control group. Results: 15 of twenty-four patients were in the first IVF-ET trial, 8 were in the second and one was in the fourth trial. The body mass index (VMI) was normalized to 21 women with vaginism with abdominal ultrasound. In 3 cases with high VKI, both folliculometry and endometrial assessments were performed with transvaginal ultrasound under sedation. Twenty-seven cycles were one ET, and eight cycles were two ET. In the 20 of thirty-nine cycles, beta human carionic gonodotropin positive was detected. Similarly, clinical pregnancy was detected in 20 cases (51.2%), while the number of cycles resulting in term and live birth was 16 (41%). In the incidents in the control group, the clinical pregnancy rate (CPR) was determined at 25 of 35 cycles (%71.4) while the live birth rate (CDO) was provided at 22 cycles (%62.8). When compared to the vaginism group, the rates of CPR (20 vs 25, p<0,09) and LBR were found similar (16 vs 22, p<0,06). The result: both clinical pregnancy and CDOs of severe vaginism infertile women with IVF-ET are similar to those of women with unexplicable infertility.

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2021
Author:  
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Journal of Academic Research in Medicine

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

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Journal of Academic Research in Medicine