Özet:

Objective: The present study investigates whether a relationship exists between the ABO and Rh blood groups and the type of rheumatic disease in patients with inflammatory rheumatic disease. Method: The present study was based on the data of 1,272 healthy subjects and 1,028 patients with an inflammatory rheumatic disease who were followed up in our clinic between June 2016 and January 2019. The type of rheumatic disease and the ABO and Rh blood groups of the participants were recorded. Results: The A blood group was more prevalent in patients with inflammatory rheumatic disease and in the healthy subjects, followed by the O, B and AB blood groups in respective order, although there was no significant difference between the ABO groups in terms of distribution(p>0.05). The Rh (+) blood group was more prevalent than Rh (-) in both groups, although there was a statistically significant difference in terms of the distribution of the Rh blood group among the groups(p<0.05). According to the results of a logistic regression analysis, the Rh (-) blood type decreases the likelihood of developing a rheumatic disease (p<0.05). Conclusions: The A and Rh (+) blood groups were more commonly observed in patients with inflammatory rheumatic diseases, followed by the O, B and AB blood groups. Furthermore, patients with the Rh (-) blood type were less likely to develop rheumatic disease. The present study may serve as a guide for future clinical studies evaluating the relationship between rheumatic diseases and blood types in terms of genetic predisposition and pathogenesis.

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