Özet:

Objective: Congenital anomaly of kidney and urinary tract (CAKUT) includes functional and structural anomalies that can cause end-stage renal disease in children. Clinical and demographic characteristics of patients with CAKUT are evaluated in this study. Methods: The files of patients who were followed up with the diagnosis of CAKUT between November 2008 and June 2011 in The Children's Hospital were reviewed retrospectively. Patient characteristics including age, gender, family history of CAKUT, consangineous marriage, and radiological imaging results were recorded. Results: The study was consisted of 232 patients 129 (55.6%) boys, and 103 (44.4%) girls. The average age was 4.4 years. A family history of CAKUT was found in 15.2% of patients and 50. 9% of parents had consanguineous marriage. Anomalies that were observed in the study included, ureteropelvic junction obstruction in 66 (28.5%), renal agenesis in 49 (21.1%), ectopic kidney in 25 (10.8%), horseshoe kidney in 25 (10.8%), multicystic dysplastic kidney in 20 (8.6%), vesicoureteral reflux in 20 (8.6%), polycystic kidney in 12 (5.2%), posterior urethral valve in 7 (3%), ureterovesical obstruction in 4 (1.7%), renal hypoplasia in 2 (0.9%), and fusion of kidneys in 2 (0.9%). Renal scarring and chronic kidney disease were present in 32 (13.8%) and 7 (3%) patients, respectively. Conclusions: Childhood CAKUT can cause serious morbidities. Cases should be followed up carefully even from the antenatal period. Early intervention of cases requiring treatment will minimize the risk of permanent renal damage.

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