Özet:

Neuroendocrine tumors arise from neuroendocrine system cells, and constitute a heterogeneous group of neoplasms. In this case report, a case of non-functional neuroendocrine tumor presented with diffuse liver metastases is discussed. In the initial evaluation, massive hepatomegaly was detected in a 62-year-old female admitted to our clinic due to symptoms of abdominal pain and bloating. There was no detectable abnormality except hyperthyroidism in the laboratory studies. Numerous hypodense mass lesions compatible with diffuse hepatic metastases were found in radiological examinations. Liver biopsy showed neuroendocrine tumor in hepatic metastases. No focus was found for the primary site of tumor. Surgical resection as a treatment option was not applicable because of her advanced age and diffuse liver metastases. Long-acting somatostatin analogue was prescribed for the patient. In the follow-up, despite reduction in the patient's symptoms, there was no change in the tumor size. In conclusion, it should be kept in mind that rare neuroendocrine tumors may present with asymptomatic diffuse liver metastases with a non-functional tumor, despite the fact that these tumors have an indolent course.

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