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Purpose: PMMA has disadvantages such as low mechanical and physical properties, despite its widespread use as a prothesis kaide material in protetic dentistry. The aim of this study is to evaluate the effect of the additives of Al2O3, SiO2 and TiO2 nanoparticles in a weight rate of 1, 3 and 5 per cent of the acrylic resin, which is polymerized by microwave energy, on the mechanical and physical characteristics such as surface hardness and surface smoothness. Tools and Methods: In our work, taking into account the recommendations of the manufacturer company, a total of seventy acrylic resin samples (65×10×3 mm) were prepared for ten different groups (n=7). After the polishing and cyling processes, the surface smoothness values (Ra) are measured by the profilometer device, while the surface hardness values are measured by the Rockwell R test. The homogenity of the obtained data was evaluated with the Kolmogorov-Smirnov test and the two-way variance analysis and Tukey HSD tests were used (α=0.05).   Results: In terms of surface smoothness values, the smoothness values of the added group of nanoparticles at 1 % were quite close to the control group (0.28-0.29), while the smoothness values of the added group at 3 % and 5 % were much higher than the critical value for microorganism retention (0.2 μm) (0.46-0.84) In terms of surface hardness values, the surface hardness values are increased as a result of the addition of nanoparticles, while the high values are found in groups added by 5% (p < 0.05). Result: Within the limits of this study, the mechanical properties can be developed by adding nanoparticles to PMMA, but as the adding percentage of nanoparticles increases (3% and 5%), the increase in the surface smoothness values of PMMA shows that the ideal filling rate is 1%.   Keywords: polymethylmethylmethylmethylmethylmethylmethylmethylmethylmethylmethylmethylmethylmethylmethylmethyl Evaluation of mechanical and physical properties of micro-wave acrylic resin reinforced with different nanoparticles Abstract Purpose: PMMA has disadvantages such as low mechanical and physical properties although it is widely used as prosthetic base material in prosthetic dentistry. The aim of this study is to evaluate the effects of adding Al2O3, SiO2 and TiO2 nanoparticles in ratios of 1, 3 and 5 wt% to microwave acrylic resins on the mechanical and physical properties such as surface hardness and surface roughness. Material and Method: A total of seventy acrylic resin specimens (65×10×3 mm) were prepared in different ten groups according to manufacturer's instructions (n=7). After polishing surface roughness values were measured by profilometer, and surface hardness values were measured by Rockwell R test. The homogeneity of the obtained data was assessed by Kolmogorov-Smirnov test followed by Two-way ANOVA and Tukey HSD test (α=0.05). Results: In terms of surface roughness values, the roughness of the groups added with 1% nanoparticle were very close to control group (0.28-0.29), whereas roughness values of 3% and 5% addition groups were found to be very high (0.46-0.84) from the critical value (0.2 μm) for microorganism involvement. In terms of surface hardness values, surface hardness values were increased as a result of nanoparticle addition, whereas the highest values were foud in 5% addition groups (p < 0.05). Conclusion: Within the limitations of this study, the mechanical properties can be improved with the addition of nanoparticles to PMMA, but the increase in the surface roughness values of PMMA with increasing nanoparticles addition ratio (3% and 5%) suggests that the ideal filler ratio is 1%. Keywords: Polymethylmethacrylate, Nanoparticle, Surface roughness, Surface hardness.

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