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Amaç: Bu çalışmada, hastanemiz Genel Yoğun Bakım Ünitesi'nde (GYBÜ) yatan hastaların kan kültürlerinden izole edilen mikroorganizmalar ve antibiyotiklere duyarlılıkları retrospektif olarak değerlendirilerek uygun ampirik tedavi seçimine yol gösterici verilerin elde edilmesi amaçlanmıştır. Gereç ve Yöntem: Hastanemizde yatan 18 yaş ve üzeri 152 hastanın kan kültürlerinden izole edilen 163 mikroorganizma ve antibiyotiklere duyarlılık sonuçları retrospektif olarak değerlendirildi. Klinikte yatan hastaların ateşli dönemlerinde alınan kan kültürleri BACTEC otomatize kan kültür sisteminde inkübe edildi. Bulgular: Üreyen mikroorganizmaların %68'ini (n=111) Gram pozitif bakteriler, %25'ini (n=40) Gram negatif bakteriler ve %7'sini (n=12) ise mantarlar oluşturmuştur. En sık izole edilen mikroorganizmalar sırasıyla koagülaz negatif stafilokoklar (KNS), Escherichia coli ve Candida spp.‘dir. Kan kültürlerinden izole edilen Gram negatif etkenlerin %7'si (n=12) E.coli, %6'sı (n=9) Klebsiella spp., %5'i (n=8) Pseudomonas spp., %4'ü (n=6) Acinetobacter spp. olarak belirlendi. Genişlemiş Spektrumlu Beta Laktamaz (GSBL) pozitifliği, E. coli izolatlarında %75 (n=9), Klebsiella spp. izolatlarında ise %78 (n=6) olarak saptandı. Sonuç: İzole edilen enfeksiyon etkenlerinin türü, sıklığı ve antibiyotik direnç durumları hakkında bilgi sahibi olup her merkezin kendi antibiyotik kullanım politikasını bu bilgiler ışığında belirlemesi morbidite ve mortalite oranlarını azaltmaya katkı sağlayacaktır.
Purpose: In this study, the microorganisms isolated from the blood cultures of the patients who are hospitalized in the general intensive care unit (ICU) of our hospital were evaluated retrospectively and it was aimed at obtaining the guiding data for the appropriate empirical treatment selection. Materials and Methods: Species distribution and antimicrobial susceptibility of 163 microorganisms, isolated from blood cultures of 152 inpatients aged 18 years and older were evaluated retrospectively. Blood cultures were taken during the febrile period of inpatients who stayed in clinic were incubated in blood culture media in the BACTEC automated blood culture system. Results: Of these microorganisms found, 68% (n=111) were Gram positive bacteria, 25% (n=40) were Gram negative bacteria, and 7% (n=12) were fungi. The most common microorganisms were coagulase negative staphylococcus (CoNS), Escherichia coli and Candida spp. Of the Gram negative agents isolated from blood cultures, 7% (n=12) were Escherichia coli, 6% (n=9) were Klebsiella spp., 5% (n=8) were Pseudomonas spp., 4% (n=6) were Acinetobacter spp. Extended Spectrum Beta Lactamase (ESBL) was detected 75% (n=9) of E.coli, and 78% (n=6) of Klebsiella spp. to isolate. Conclusion: Epidemiological information about species distribution and antibiotic resistance of the isolated infectious agents and will contribute to the determination of their antibiotic use and to decrease the morbidity and mortality rates.
Purpose: In this study, the microorganisms isolated from the blood cultures of the patients who are hospitalized in the general intensive care unit (ICU) of our hospital were evaluated retrospectively and it was aimed to obtain the guiding data for the appropriate empirical treatment selection. Materials and Methods: Species distribution and antimicrobial susceptibility of 163 microorganisms, isolated from blood cultures of 152 inpatients aged 18 years and older were evaluated retrospectively. Blood cultures were taken during the febrile period of inpatients who stayed in clinic were incubated in blood culture media in BACTEC automated blood culture system. Results: Of these microorganisms found, 68% (n=111) were Gram positive bacteria, 25% (n=40) were Gram negative bacteria, and 7% (n=12) were fungi. The most common microorganisms were coagulase negative staphylococcus (CoNS), Escherichia coli and Candida spp. Of the Gram negative agents isolated from blood cultures, 7% (n=12) were Escherichia coli, 6% (n=9) were Klebsiella spp., 5% (n=8) were Pseudomonas spp., 4% (n=6) were Acinetobacter spp. Extended Spectrum Beta Lactamase (ESBL) was detected 75% (n=9) of E.coli , and 78% (n=6) of Klebsiella spp. ısolate. Conclusion: Epidemiological information about species distribution and antibiotic resistance of the isolated infectious agents and will contribute to the determination of their antibiotic usage and to decrease the morbidity and mortality rates.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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