Özet:

I am. The purpose of this study was to compare the effects of frequently used anesthetic agents, which are sevoflurane, isoflurane and propofol on thyroid metabolism during and after anesthesia. The Methods. The study was done with euthyroid patients; 22 women and 23 men (total n: 45) aged 28-70. Patients were divided into three groups, one as sevoflurane (n=15), one as isoflurane (n=15) and one as propofol (n=15). Preoperatively, 15 minutes after induction, 30 minutes after surgery and postoperatively in the 30th minute blood samples were taken from all of the patients. The variations of f T, f T and TSH levels were studied. The results. f T levels started to decrease at induction with all anesthetic agents and the decrease was most evident in postoperative period. On the other hand f T levels increased in all groups after surgical insicion and postoperatively. However, the increase in f T levels with propofol anesthesia was significantly lower than the f T levels with inhalation agents. In all groups, TSH levels were found higher only in the postoperative period. and Conclusion. With these findings; propofol can be a more suitable agents than isoflurane and sevoflurane in anesthetic procedures for emerging patients with hyperthyroidism.

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