Abstract:

The prevalence of chronic diseases that occur as a result of irreversible loss of function of one or more systems in the human body and require lifelong treatment is increasing in the world. The fetus in the intra-uterine environment is in a state of continuous development. It is reported that the deoxyribonucleic acid (DNA) sequence of the fetus is reprogrammed depending on the maternal factors exposed during the fetal period and various environmental stressors. According to the fetal programming hypothesis, the stresses which the fetus exposed are the basis of chronic diseases in adulthood. In the present review, fetal pro-gramming of chronic non-communicable diseases that are common in the world and some factors affecting programming were examined.