Abstract:

Purpose: The acute coronary syndrome (ACS) covers a wide range of clinical conditions from ST segment upward myocardial infarction to unstable angina pectoris (UAP). UAP cannot be detected by any biobelirector in the Emergency Service Clinic. The trombocytes lymphocytes rate (PLR) is shown as a potential sign for determining excessive trombocytic activity and inflammation in heart disorders. Syntax score (SXscore) is an anatomical score system based on coronary angiography that not only measures the severity and complexity of the injury, but also predicts cardiovascular results, including mortality in patients with ACS. The aim of this study is to reveal the predictive value of PLR in these patients by comparing the trombocyt lymphocytes rate with SXscore in UAP patients. Material and Method: Working group was formed from patients diagnosed with UAP seeking emergency service and adult patients diagnosed with UAP in emergency service. The control group consists of healthy adults with no chronic disease. The study group applied coronary angiography to patients with ACS suspicion and the Syntax Score was calculated for each patient. PLR levels were compared between the study and control group and the Syntax scores were compared with the PLR levels of the study group. Results: The average PLR levels were 122.89±52.44 in the UAP group and 104.21±22.85 in the control group (p: 0.005). When the PLR level was 113.98, it was found to have a sensitivity of 55.8%, a specificity of 66.7%, and a negative correlation with SXscore (r=- 0.325; p: 0.004). The result: Patients with UAP have seen a significant increase in PLR levels. PLR can be considered as a new indicator in the prediction of the severity of UAP. However, the coronary vascular damage was found ineffective in the assessment.

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