Özet:

The aim of our study was to investigate the correlation between insulin resistance and hormonal parameters of insulin resistance on non-obese and obese patients with polycystic ovarian syndrome (PCOS). METHODS: 78 women patients with age range 21 to 40 diagnosed with PCOS based on the clinical and endocrine features were included in our study. PCOS was diagnosed according to the reviewed Rotterdam criteria. PCOS patients were studied in two groups: Obese patients (the patients that body mass index over 25) non-obese patients (the patients that body mass index under 25). Results: It has been detected, fasting insulin, total testosterone and HbA1c levels were significantly higher and also HDL levels were significantly lower in the obese group. Besides, QUICKI and fasting glucose / fasting insulin levels have been detected significantly low, HOMA-IR was significantly higher in the obese group.In the non-obese group LH / FSH ratio is correlated with HOMA-IR and QUICKI and also total testosterone levels are correlated with QUICKI. In addition, it has been noted that the insulin resistance is not correlated with the FSH level. PCOS patients Impaired glucose tolerance and the prevalence of DM are 5 times greater than the general population. PCOS is seen more frequently in type 2 DM patients. Discussions and conclusions: We suggest insulin resistance screening in all PCOS patients. However, if this is not possible, at least all patients that VKI levels above 25, should be screened. We think that, LH level in obese patients with PCOS is important to predict the insulin resistance.

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