Abstract:

Aim: To compare mean platelet volume (MPV) values and platelet counts of normal pregnancies and patients with missed abortions to determine whether hematological parameters such as MPV and platelet counts (PLT) can predict unsuccessful pregnancy particularly missed abortion. Material and Methods: This retrospective case-control study investigated the hematological parameters of patients diagnosed with missed abortion and the control group. Among 476 cases, 238 participants with missed abortion were included in the study group and 238 healthy pregnant women were included in the control group. The mean age of the missed abortion group was 33.50 and the mean age of the control group was 32. Result: Age showed a significant difference between the two groups (p = 0.01). Gestational age was higher in the missed abortion group than that in the control group (p < 0.001). Significant differences in gravida (p < 0.001) and parity (p = 0.002) were observed. Smoking was higher in the missed abortion group than that in the control group (p < 0.001). RDW-SD (p < 0.001) and hematocrit (p = 0.032) showed significant differences between groups. There was no significant correlation between MPV (p = 0.155; OR = 1.097; CI = 0.966_1.247), PDW (p = 0.695; OR = 0.991; CI = 0.947_1.037), PCT (P = 0.468) and missed abortion. Conclusion: Hematological parameters such as MPV may not be used as a screening or diagnostic test for unsuccessful pregnancies particularly missed abortion as shown in the current study.

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