Objective: To investigate the prevalence of the metabolic syndrome in obese children and adolescents who presented at our endocrine clinic.Material and Methods: We included 92 children and adolescents between the ages of 6-18 who underwent a standard dose of oral glucose tolerance test with a diagnosis of exogenous obesity. Their medical records were analyzed retrospectively. We modified the criteria of metabolic syndrome (MS) for adults defined by the NCEP/ATP III and WHO with the pediatric age reference values. MS was diagnosed in those with three or more criteria.Results: 30 (32%) patients were diagnosed with MS. Among these patients with MS, we determined insulin resistance (IR) in 18, impaired fasting glucose in 6, impaired glucose tolerance in 9 and diabetes in 2 patients. Hypertriglyceridemia was found in 12 of 27 dyslipidemic MS patients, low HDL-C in two, hypertriglyceridemia and low HDL-C in nine, and hypertriglyceridemia and LDL-C elevation in three patients. LDL-C elevation was detected only in one patient. There was systolic hypertension in 12 patients. Ten patients had diastolic hypertension. Hepatosteatosis was determined by USG in 10 of 21 patients with MS.conclusion: Obese children have a high prevalence of MS. These patients possess multiple risk factors for the development of diabetes and cardiovascular disease in the future such as hypertension, dyslipidemia and insulin resistance
Objective: To investigate the prevalence of the metabolic syndrome in obese children and adolescents who presented at our endocrine clinic.Material and Methods: We included 92 children and adolescents between the ages of 6-18 who underwent a standard dose of oral glucose tolerance test with a diagnosis of exogenous obesity. Their medical records were analyzed retrospectively. We modified the criteria of metabolic syndrome (MS) for adults defined by the NCEP/ATP III and WHO with the pediatric age reference values. MS was diagnosed in those with three or more criteria.Results: 30 (32%) patients were diagnosed with MS. Among these patients with MS, we determined insulin resistance in 18, impaired fasting glucose in 6, impaired glucose tolerance in 9 and diabetes in 2 patients. Hypertriglyceridemia was found in 12 of 27 dyslipidemic MS patients, low HDL-C in two, hypertriglyceridemia and low HDL-C in nine, and hypertriglyceridemia and LDL-C elevation in three patients. LDL-C elevation was detected only in one patient. There was systolic hypertension in 12 patients. 10 patients had diastolic hypertension. Hepatosteatosis was determined by USG in 10 of 21 patients with MS.conclusion: Obese children have a high prevalence of MS. These patients possess multiple risk factors for the development of diabetes and cardiovascular disease in the future such as hypertension, dyslipidemia and insulin resistance
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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