Özet:

Objective: Indirect hyperbilirubinemia is an important problem in newborns and phototherapy has an important role in treatment. The aim of this study is to evaluate the effects of phototherapy on hematological parameters in newborns with indirect hyperbilirubinemia. Materials and Methods: January 2021- March 2022, 60 newborns (term = 30 and preterm = 30) diagnosed and treated for indirect hyperbilirubinemia were included in this study. Results: Twelve of the term babies (40%) had either Rh (n = 3) or ABO incompatibility (n = 9). Ten of the preterms (33%) had either Rh (n = 3) or ABO incompatibility (n = 7). The median values of phototherapy time of term and preterm newborns were 24 (range, 6-40) and 11 hours (range, 4-36), respectively. After phototherapy, WBC and RBC counts, Hb, MCV and RDW values of term newborns decreased significantly. In preterm newborns white blood cell count, red blood cell count, hemoglobin, mean corpuscular volume of red blood cells, red blood distribution width (WBC and lymphocyte, counts and Hb, MCV and RDW) values decreased significantly, while a statistically significant increase in mean corpuscular hemoglobin concentration (MCHC) values and the percentage of monocyte counts were determined. Conclusion: Our study suggests that phototherapy has various effects on hematological parameters. Some of these effects can be explained by Rh or ABO incompatibility, but prospective studies including more patients are needed to explain the changes in hematological parameters in newborns without Rh or ABO incompatibility.