Özet:

Background: Magnesium (Mg) is essential for life and plays a key role in the human body's various biochemical and physiological processes. Hypomagnesemia is common in all hospitalized patients, especially with co-existing electrolyte abnormalities in critically ill patients. Hypomagnesemia, if not diagnosed on time and appropriately treated, can cause serious and potentially fatal complications and is associated with increased mortality.Aim and Objectives: To study hypomagnesemia in critically ill patients and its correlation with patient outcomes considering the following parameters: Age, Sex, Diabetic status, Association with other lab parameters, APACHE II score, Need for ventilator support, Length of stay in ICU, Total stay in the hospital, Mortality.Materials and Methods: The study was a prospective study done in the Department of General Medicine (Medical ICU), Sri Ramachandra Medical College and Research Institute from September 2016 to August 2017. A thorough clinical examination was done; clinical data were recorded into the EXCEL case sheet. Serum calcium, serum potassium, ABG, along with other basic labs was sent for all patients. APACHE II score was calculated and all parameters were entered into an excel sheet. The results of the study were analyzed and statistical data was summarized using SPSS 17 software. Pearson Correlation, Kendall Tau B, Student t-test, and ANOVA were done for specific variables.Results: A total of 1067 patients admitted in ICU between September 2016 to August 2017 were taken into the study out of which 169 patients had hypomagnesemia (< 1.8 mg/ dl). Various correlations were analyzed for age, sex, diabetic status, APACHE II score, serum calcium, serum potassium, ventilator requirement, ICU stay, hospital stay, and outcome. A total of 169 patients out of 1067 patients had hypomagnesemia in the present study (15.83%). The minimum magnesium value was 0.8 mg/dl and the maximum value was 1.7 mg/dL. The present study highlighted the importance of hypomagnesemia in intensive care unit and its outcome with various parameters. The present study showed that hypomagnesemia is associated with increased APACHE II score, increased incidence of ventilator requirement and higher mortality.Conclusion: Magnesium is an unrecognized cation in critically ill patients. The incidence of hypomagnesemia in the present study was less compared to other studies done in medically ill patients. Hypomagnesemia correlated well with APACHE II score, ventilator requirement, and mortality, which was statistically significant. 

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