Abstract:

The aim of this study was to identify possible mechanisms of action of leptin in the body, with the exercise of obesity path physiology. Leptin is a hormone synthesized mainly by adipocytes, responsible for the control of energy balance. Serum leptin levels are higher in obese compared with lean subjects, correlating directly to body fat percentage, characterizing resistance to leptin. Non-pharmacological strategies that aims at reducing body weight using diet and exercise as primary tools. Studies show that obese individuals exercise chronic (> 8 weeks) is able to reduce the plasma concentration of leptin, independent of gender and the type (aerobic or resistance). However, this reduction is associated with reductions in various anthropometric index (body weight, body fat percentage, fat mass, BMI, waist circumference and waist-hip ratio). Studies evaluating the plasma concentration of leptin after a session of moderate exercise in obese subjects did not identify significant changes. Therefore, it seems necessary that physical exercise promotes significant changes in body composition that are observed changes in plasma leptin. This fact can be attributed to reduced secretion of leptin by adipose tissue due to a reduction in body fat associated with exercise.

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