Abstract:

Our aim in the study is to retrospectively evaluate the histopathological characteristics of central nervous system infections in the light of literary information. In the years 1998-2002 the Court Medical Institute of Morg specialized department of the autopsy and detected the central nervous system infection 103 cases were taken to study. Our cases have been evaluated in terms of age, gender, causes of death (natural and traumatic deaths) and the histopathological characteristics of the infection detected in the brain. The study found that 50.4 percent of the 103 incidents were natural and 49.6 percent were dead as a result of developing trauma-related complications. 85 of our cases (83.3%) were men and 18 (16.6%) women. Histopathologically, menenjitis was detected in a total of 73 cases (70.87) . In this group, 60 cases (58.25%) were considered acute pyogenic (bacterial) menenjitis, 8 cases (7.76) acute aseptic (viral) menenjitis, 5 cases (4.85) granulomatosis menenjitis. In one of the occurrences of granulomatosis menenjitis (%20) the nocardial infection, which is also accompanied by brain disconnection, in four (%80) tuberculosis infection was detected. In 19 cases (18.44) the infection was found. In this group, 8 incidents were assessed as non-specific encephalitis (7.76%), 5 incidents (4.85) viral encephalitis associated with gonorrhea, 1 incidence (0.97) encephalitis associated with HIV, 1 incidence (0.97) progressive proprietary lokoencephalopathy, 4 incidents (3.88) Prion disease (Jacob-Creutzfeld). In our series, 3 cases (2.91) meningoensephalitis, 6 cases (5.82) brain abscess, and 2 cases (1.94) non-specific cerebritis were detected. The pathology of infectious diseases in the central nervous system is quite complex and often contains tables covered with each other. As a result, a multidisciplinary laboratory research in the pathology of infectious diseases is necessary.

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