Abstract:

The benzaldehyde and their derivatives have a good antimicrobial properties. Our research aim is to improve the antimicrobial effect, different derived from 3-Alkil/aril-4 triozole and metoksibenzoksi. The synthesized triazoles were characterized by spectroscopic techniques, such as, 1H NMR, 13C NMR, UV absorption spectra, and mass spectra (MS). We were mesured their antibacterial activities in vitro against Bacillius  subtilis, Yersinia enterocolitca, Bacillus cereus, Staphlacoccus aureus, Esherichia coli, Pasterulla multicida, Klepsiella pnemonias. The synthesis of a series of etoksibenzilidenamino derived 1,2,4-triazoles has been realized with good yields using the CuAAC of a variety of alkynyl heterocycles, alkynyl carbohydrates or alkynes. The structures of the obtained compounds were confirmed by NMR spectroscopy (1H and 13C) and mass spectrometry. Overall, the molecules are not showed very antibacterial activity, but our antibiotic showed that important antibacterial activity.

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