In this retrospective study, we evaluated 221 febrile neutropenia (FN) episodes in 75 pediatric leukemia cases during empiric antibiotherapy in terms of antibiotic modifications, culture results, treatment period and mortality retrospectively. One hundred and seventeen (52.9%) episodes were microbiologically and/or clinically documented infections. During febrile neutropenia attacks, 14.4% of patients had bacteriemia. Of isolated microorganisms, 73.5% gram-positive, 17.6% were gram-negative and 8.8% fungal pathogens. Fever resolved after mean 7.2 days and mean antibiotic administration time was 13 days. Granulocyte-colony stimulating factor (G-CSF) was used in 102 episodes (46.2%) of FN. Eight patients (%3.6) died during a FN episode
Field : Sağlık Bilimleri
Journal Type : Uluslararası
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