Özet:

Objective: To investigate obstetric and perinatal outcomes among pregnant female survivors of adolescent and young adult cancers. Materials and Methods: A retrospective analysis of maternal and perinatal outcomes of 68 pregnant women with a history of cancer who received antenatal care at the Cerrahpasa Medical Faculty Obstetric and Gynecology Department between January 2000 and  December 2015 was carried out. Perinatal and maternal outcomes were evaluated according to cancer type, timing of cancer diagnosis, and treatment modality. The distribution of cancer types, the age at which the cancer was diagnosed, the treatment modalities, and the duration of follow-up were analyzed. Maternal and perinatal outcomes were evaluated. Results: The most frequently encountered tumor types in pregnant women with a history of cancer were thyroid cancers (26.5%), hematologic malignancies (22.5%), and genital cancers (18%). The mean maternal age was 31.7±5.5 years, and the frequency of nulliparity was 48.5%. The mean gestational age at delivery was 37.5±2.5 weeks, the mean birth weight was 3020±717 g, and the frequencies of delivery before 37 and 34 weeks were 12.1% and 8.8%, respectively. The incidences of ceaserian section, fetal growth restriction, preeclampsia, and gestational diabetes were 77.2%, 5.8%, 2.9%, and 8.8%, respectively, in women with a history of cancer. There were two miscarriages and three terminations of pregnancy in women who had survived cancer. The lowest mean age at the time of cancer diagnosis was observed for haematological cancers (22.5±6.6). There were no congenital anomalies in our group. Conclusion: Cancer survivors who became pregnant after cancer treatment had good obstetric outcomes. Pregnancy follow-up of these patients should be carried out by a multidisciplinary team at tertiary centers.

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