Özet:

Purpose: The object of this randomized and double-blinded study was to compare the effectiveness of intrathecally applied levobupivacaine at different doses with or without morphine added in elective Cesarean section operations with spinal anesthesia. Materials and Methods: The study was planned as prospective, randomized and double-blinded in ASA I-II group of sixty women who were 37-42 weeks pregnant and applied spinal anesthesia for cesarean section. Patients were randomized into two groups. 12.5 mg (3 ml) levobupivacaine to group L, 10 mg levobupivacaine + 0.1 mg morphine (3 ml) to group LM were applied intrathecally. Sensory and motor block durations, postoperative immediate 24 hour VAS pain scores, time to the first need for analgesia, hemodynamic and respiratory parameters, sedation levels, APGAR scores, patients' satisfaction and complications were recorded. Results: No significant difference was found between groups in terms of time to motor block formation and termination, time to sensory block formation and its two segment decline, and patients' satisfaction. Rescue analgesic need for the first time in group L was earlier compared to group LM (158.6 ± 31.8 minutes and 176.6 ± 37.16 minutes respectively). Conclusion: Despite dose reduction, its combination with low-dose morphine was resulted in prolongation of spinal analgesia without significant increase in the frequency of side effects and complications with similar anesthesia and analgesia levels.