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Overin Granüloza hücreli tümörü:30 hastanın klinik ve patolojik özelliklerinin analizi
2023
Journal:  
Türk Jinekolojik Onkoloji Dergisi
Author:  
Abstract:

Amaç: Overin granüloza hücreli tümörleri (GHT), overin seks kord- stromal bileşeninden kaynaklanan ve sıklığı az olan kanserlerinden biridir. Biz bu çalışmada granüloza hücreli over tümörlerinin nadir görülmesinden dolayı kendi kliniğimizdeki hastaların klinik ve patolojik özellikleri ile birlikte bu hastaların yönetimindeki deneyimimizi anlatmayı amaçladık. Yöntem ve Gereçler: Çalışmamıza histopatolojik tanısı granüloza hücreli tümör olan 30 hasta dahil edildi. Bu hastaların elektronik medikal dosyaları; demografik ve klinik özellikleri, tümörlerin patolojik özellikleri, cerrahi evreleri, uygulanan tedaviler, nüks durumları ve sağ kalımları bakımından retrospektif olarak incelendi. Bulgular: Hastaların ortalama yaşı 51,1 (13-77) idi ve en sık kliniğe başvuru şikayeti karın ağrısıydı (%40). Dört hastaya (%13,3) fertilite koruyucu cerrahi yapılırken 24 hastaya cerrahi evreleme yapıldı. Fertilite koruyucu cerrahi yapılan hastalardan sadece bir tanesinin gebelik istemi vardı ve sağlıklı tekil bir çocuk doğurdu. Hastaların %86,6’sı evre 1’de tanı aldı. Hastaların ortalama takip süresi 85 (8-252) aydı. Takip sırasında 5 hastada nüks gelişti ve bunlardan iki tanesi öldü. 5 ve 10 yıllık genel sağ kalım sırasıyla %96,7 ve %93.3 olarak saptanırken; 5 ve 10 yıllık hastalıksız sağ kalımın her ikisi de %90 olarak saptandı. Sonuç: Sonuç olarak çalışmamıza katılan hastaların analiz sonuçlarının daha önce yapılan çalışmalarla uyumlu olduğunu saptadık.

Keywords:

Overin Granulose cell tumor: 30 clinical and pathological characteristics of the patient
2023
Author:  
Abstract:

Purpose: Overin granulose cell tumors (GHT) are one of the cancers that are caused by the sex cord-stromal component of overin and are less frequent. In this study we aimed to explain our experience in the management of these patients along with the clinical and pathological characteristics of patients in our own clinic due to the rare occurrence of granulose cell over tumors. Methods and tools: Our study included 30 patients with a granulose cell tumor with a histopathological diagnosis. The electronic medical files of these patients were studied retrospectively in terms of demographic and clinical characteristics, pathological characteristics of tumors, surgical stages, therapies applied, disease and survivors. Results: The average age of patients was 51.1 (13-77) and the most frequent clinic complaint was stomach pain (40%). Four patients (13.3%) were subjected to fertility protection surgery, while 24 patients were subjected to surgery. Only one of the patients performed fertility-protectional surgery had a pregnancy request and gave birth to a healthy single child. 86.6% of patients were diagnosed in stage 1. The average follow-up period of patients was 85 (8-252) months. During the follow-up, 5 patients developed nuts, and two of them died. The overall survival rate of 5 and 10 years was 96.7% and 93.3% respectively, while the total survival rate of 5 and 10 years without disease was both 90%. Result: As a result, we found that the analysis results of the patients who participated in our study were consistent with previous studies.

Keywords:

2023
Author:  
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Türk Jinekolojik Onkoloji Dergisi

Journal Type :   Uluslararası

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Article : 30
Türk Jinekolojik Onkoloji Dergisi