Özet:

Context: Corona virus disease (COVID-19) is an infectious disease. About 5% become critically ill and need intensive care. Being a novel disease, there is need of research on safe and effective management especially in Intensive care unit (ICU). Aims: To know epidemiology and management of adult COVID-19 disease patients in ICU. Settings and Design: An observational study done in adult COVID-19 patients admitted in ICU of a tertiary care hospital. Methods and Material: Purposive sampling method was used and data in 241 adult COVID-19 patients was collected on sociodemograpy, comorbidities, clinical and radiological severity, risk categorization (by Quick Sequential Organ Failure Assessment (qSOFA) and Systemic Inflammatory Response Syndrome (SIRS)). Biochemical investigations done, treatment given and outcome were recorded. Statistical analysis used: Data analysed using SPSS 20. Chi-square test and Mann Whitney U test was used. P<0.05 was considered statistically used. Results: Out of 241 Patients, 69(28.6%) died. Mortality was significantly high in age group > 60 years. Patients with higher Lactate dehydrogenase (LDH), serum ferritin and procalcitonin levels, have high proportion of mortality. Patients with Diabetes mellitus (41.1%), cardiovascular disease (6.2%), CTSS score >18 (44.7%) and SIRS score 2-4(32%) have high mortality. Inotropes, anticoagulation, anti-inflammation and convalescent Plasma therapy was given in and awake proning practiced in 41.1%, 72.6%, 73.4%, 36.9% and 23.6% respectively. Conclusions: ICU Mortality of COVID-19 patient was 28.6%. Patients with age > 60 years, diabetes mellitus, cardiovascular disease, higher LDH, serum ferritin and procalcitonin have, significantly higher prevalence of mortality.

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