Özet:

INTRODUCTION: The aim of the study was to compare the safety of the laparoscopic and open method for endometrial cancer staging METHODS: Between January 2015 and August 2017, we reviewed 121 women with endometrial cancer treated by open (n=81) or laparoscopic (n=40) approach, retrospectively. Two groups were compared in terms of operating times, intraoperative and postoperative complications, perioperative and postoperative features such as hemoglobin values, the lengths of hospital stay, and adjuvant therapy. All of the patients underwent a hysterectomy and bilateral salpingo-oophorectomy; and when indicated, omentectomy and lymphadenectomy were performed. RESULTS: There were no significant differences between the two groups with regard to the number of parities, body mass index, menopausal status, age, the American Society of Anesthesiologists (ASA) scores, the requirement of lymphadenectomy, and hospital stay. There were significant statistical differences between groups in terms of operation time and difference of hemoglobin (p<0.001, p=0.013; respectively). Laparoscopic surgery had a longer operative time than laparotomy, and difference of hemoglobin in the laparotomy group is more than the laparoscopy group. Patients who underwent staging with laparotomy had bowel injury (1.2%), wound infection (13.6%), and postop ileus (8.6%) while in the laparoscopy group patients had wound infection (2.5%) and postop ileus (5%). There were no statistically significant differences between the two groups in terms of the intraoperative (p=1) and postoperative complications (p=0.101 for wound infection, p=0.716 for postop ileus). The groups were similar in terms of the histological grade, FIGO stage, histologic subtype, the rate of lymphovascular invasion, the depth of myometrial invasion, the total number of lymph nodes resected in lymph node dissections, the rate of lymph node metastasis, the location of the tumor, cervical stromal invasion, and the adjuvant therapy such as chemotherapy and brachytherapy. None of the patients in both groups had a recurrence and long-term lymphatic complication such as lymphocyst, lymphedema. DISCUSSION AND CONCLUSION: Our current data demonstrated that the laparoscopic approach can be performed without loss of safety with similar complication rates in patients with endometrium cancer. Additionally, the laparoscopy was not inferior to the laparotomy in terms of efficacy.

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