Objective: The classic definition of being small for gestational age (SGA) may lead to inadequate evaluation if there are varying degrees of growth restriction in preterms. In this study, we aimed to investigate the effectiveness of moderate or severe SGA on mortality in very low birth weight infants. Methods: In this retrospective study, 711 premature babies with birth weight <1500 g born in our hospital between 2013 and 2017 were included. According to the gestational week, with a birth weight <10 percentile were grouped as SGA, between 10-19 percentile were grouped as moderate SGA (M-SGA) and with >20 percentile were grouped as AGA. Fenton growth curve was used to determine percentile. Results: In the study, 34, 46 and 631 babies were included in the SGA, M-SGA and AGA groups, respectively. The median birth weight was 660 g (560-720) in the SGA group, 800 g (720-870) in the M-SGA group and 1080 g (920-1245) in the AGA group (p<0.001). Mortality rates were higher in SGA (44.1%) and M-SGA (15.2%) groups than in AGA (11.9%) groups (p<0.001). In logistic regression analysis, early neonatal sepsis [Odds ratio (OR): 2.5, 95% confidence interval (CI): 1.5-4.3], severe intraventricular bleeding (OR: 3.8, 95% CI: 2.08-6.77) and being SGA (OR: 7.08, 95% CI: 2.5-14.7) are found as independent risk factors for mortality. The presence of moderate SGA was not detected as an independent risk factor for mortality. Conclusion: SGA with accompanying prematurity involves more risk for morbidity and mortality. The presence of moderate SGA in very low birth weight infants may also increase mortality. Further studies are needed with new classifications prepared considering the severity of SGA.
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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