Özet:

Purple of Henoch-Schönlein (HSP) is the most common vasculitis in childhood. In this study, we aimed at retrospective examination of clinical findings, laboratory findings and treatment results, especially in children with HSP that were treated in our clinic or in which we were traced in the clinic. Method: This study included 50 patients from the University of Health Sciences, Istanbul Bağcılar Education and Research Hospital, the Children's Health and Diseases Clinic, who received HSP diagnosis and had at least 9 months of monitoring. Results: The patients received the study were between 3 and 16 years of age (an average of 6.9). 31 patients with kidney constipation were between 5 and 16 years of age (an average of 10.1). 30% of the cases were girls (n=15), 70% men (n=35). In patients with kidney constipation, 11 (35 percent) were girls and 20 (65 percent) men. The disease was observed more frequently in men as consistent with literature (p<0,05). In 10 cases (%20) the season of the disease was determined as winter, in 11 cases (%22) spring, in 10 cases (%20) summer, in 19 cases (%38) autumn. In all cases, skin shutdown (100%), gastrointestinal shutdown (58%) in 29 patients, joint shutdown (42) in 21 patients, kidney shutdown (62) in 31 patients were detected. The number 32 of our patients first applied to central nervous system suspension. In the study, 13 patients (26 percent) were diagnosed with nonsense. Renal symptoms occurred in 64.6 percent of patients in the first 4 weeks of the disease, and later in 35.4 percent. All 31 patients with renal constipation were diagnosed with hematuria, 5 (%10) proteinuria, 2 (%4) mass proteinuria, 2 (%4) urine, high creatine, 4 (%8) high blood pressure. In 29 patients diagnosed gastrointestinal attitude, 23 (79) were found to have a renal attitude. In the remaining 21 patients, 8 (38%) were diagnosed with renal attitude. These results were found meaningful in terms of the observation of gastrointestinal and renal holdings together (p<0,05). The result: HSP can be seen frequently in the autumn, where upper respiratory infections show increased, the most common outcome after purpura is renal holding, and renal holding can also appear with tables such as hematuria, proteinuria, nefrotic syndrome, hypertension, acute kidney failure. It was found that renal holding occurred in the first 4 weeks, especially in patients with gastrointestinal holding, increased the likelihood of renal holding. Having in mind the wide spectrum of renal attitude of patients with HSP, the importance of their tracking and the monitoring of the potential serious renal disease in proteinuric, hypertensive cases, as well as in IgA nefropathy, the treatment of angiotensin receptor blocks can result in extremely positive results.

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