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COVID-19 hastalığının immünopatolojisi ve immünolojisindeki güncel veriler
2020
Journal:  
Eurasian Journal of Veterinary Sciences
Author:  
Abstract:

31 Aralık 2019 tarihinde Çin Halk Cumhuriyeti?nden dünyaya yayılan Ağır Akut Solunum Sendromu (severe acute respiratory syndrome- SARS) koronavirüs (CoV)2?nin neden olduğu hastalık tablosu koronavirüs hastalığı-2019 (Coronavirus Disease 2019-COVID-19) olarak adlandırılmıştır. Bu derlemede, SARS-CoV-2?nin doğal ve adaptif bağışıklık ile etkileşiminin güncel makaleler ile detaylı bir şekilde ele alınması amaçlanmıştır. COVID-19 geçiren ağır vakalarda, immünolojik homeastazisin bozulduğu ve neticesinde sitokin fırtınasının geliştiği rapor edilmiştir. COVID-19 geçiren hastalarda artan viral yük, lenfopeni, eozinopeni, azalan trombosit sayısı hastalığın patolojisi ve şiddetinin derecesi ile ilişkilendirilen önemli belirteçler olmuştur. Koruyucu antikorların beklenenden hızlı bir şekilde azalması ise, tekrarlayan enfeksiyonlara karşı daha dikkatli olunmasının zorunlu olduğunu göstermektedir. Bu neden ile etkin, güvenli aşı ve antiviral tedaviler bulunana kadar COVID-19 hastalığı ile sürdürülebilir ve disiplinli mücadele şarttır.

Keywords:

Current data in immunopathology and immunology of COVID-19
2020
Author:  
Abstract:

On December 31, 2019, the disease chart caused by the severe acute respiratory syndrome (SARS) coronavirus (CoV)2 (Coronavirus Disease 2019-COVID-19) was called Coronavirus Disease 2019. In this collection, the aim is to detail the interaction of SARS-CoV-2 with natural and adaptive immunity with current articles. In severe cases passing COVID-19, it has been that immunological homeasthesis has been deteriorated and a result of the development of a cytokine storm. Increased viral burden, lymphopenia, eozinopenia, reduced number of thrombocytes in patients with COVID-19 have been important indicators associated with the pathology and severity of the disease. If protective antibodies decrease faster than expected, it indicates that it is necessary to be more careful against recurring infections. For this reason, effective, secure vaccines and antiviral treatments are a sustainable and disciplined fight against COVID-19 disease until it is found.

Keywords:

0
2020
Author:  
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Eurasian Journal of Veterinary Sciences

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

Metrics
Article : 1.407
Cite : 1.279
2023 Impact : 0.068
Eurasian Journal of Veterinary Sciences