Özet:

Purpose: In the evaluation of the thyroid nodes, the clinical characteristics are the methods used in the prediction of thyroid thin injection aspiration biopsy (IAB) and ultrasound malignity. It is especially important to know the incidents of false negative and false positive of the thyroid IAB in order to be able to make a surgical decision in injuries to reduce such as follicular neoplasm and its importance uncertain atypic. Our purpose in this study is to study the ultrasound characteristics of the thyroid nodes found to be histologically malignant and to evaluate the histopathological correlations of cytologists to the indication found in the thyroid IAB. Methods: From January 2010 to January 2012, the demographic characteristics of 154 patients with thyroidectomy caused by nodular guatr, cytology and histopathology results, the ultrasound characteristics of the nodules, pre-operative TSH values were evaluated retrospective. Results: 104 (67,5%) of the patients involved in the study found that the histopathology result was benign and 50 (32,5%) malign. There is no difference between age and gender between the two groups. As a result of histopathology, the levels of TSH in the benign group were significantly lower compared to the malign group. In this study, the thyroid IAB sensitivity in our clinic was calculated at 90.7%, the specificity at 72.2%, the positive predictive value at 62.7%, and the negative predictive value at 93.8%. The diagnostic accuracy of the thyroid IAB was found at 78.5%. The Unknown Atipi frequency was estimated at 7%, and 25% of these injuries were histopathologically malignant. When ultrasonographic characteristics were evaluated, the independent risk factors for malignant histopathology were found as hypoecogenicity (OR=2.3 p<0.05), microcalcification presence (OR=2.5 p<0.05), and peripheral and central bleeding (OR=11 p<0.05). The results of the cytology and histopathology of the incidental thyroid nodes in our study are consistent with the literature. Hypoekoic nodes containing microcalcification and indicating the peripheral and central bleeding pattern are more likely to be malignant.