Özet:

Objective: We aimed to determine the relationship between vitamin D levels and benign prostate hyperplasia BPH) related lower urinary tract symptoms (LUTS) in men over 40 years of age. Material and Methods: The study was conducted prospectively between January and April 2019 and included 48 patients who presented to the outpatient clinic with lower urinary tract symptoms and who had not received medical or surgical treatment due to BPH (BPH group) and 52 healthy men (Control group) who did not have lower urinary tract symptoms and applied to the outpatient clinic for routine urological control. Vitamin D, total PSA, total testosterone values, IPSS scores, prostate volumes and maximum urinary velocity in uroflowmetry (Q max) of both groups were evaluated. Results: The mean age of 48 patients with benign prostatic hyperplasia in BPH group was 65.37 ± 7.24 and in control group without urinary tract symptoms was 64.09 ± 8.22. There was a statistically significant difference between BPH and control groups in terms of the mean values of 25 hydroxy vitamin-D values (p< 0.001). When the patients diagnosed with BPH were examined according to their subgroups; there was no statistically significant difference in terms of 25 hydroxy vitamin D level between moderate LUTS (33 patients) and severe LUTS (15 patients) groups(p> 0.05). Conclusion: Our study has shown that in patients with BPH and LUTS, 25 hydroxy vitamin D levels were lower than those in the similar age group without any complaints. Based on this, it was thought that there might be an improvement in the symptoms of patients with increasing vitamin D levels. To reach a final judgment on this subject, larger number of randomized controlled prospective studies are needed.

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