Özet:

OBJECTIVE: In this study, it was planned to investigate the effectiveness of biopsy parameters of patients who underwent transrectal ultrasonography-guided prostate biopsy in predicting the results of subsequent radical prostatectomy. MATERIAL AND METHODS: Between June 2021 and June 2023, patients (n=106) who underwent open retropubic radical prostatectomy after prostate cancer was diagnosed in transrectal ultrasonography-guided prostate biopsy (TRUS-Bx) were included in the study. The pathology findings detected in prostate needle biopsy and those found in radical prostatectomy material were compared. RESULTS: The consistency for tumor localization in biopsy and radical prostatectomy specimens was %62,2 (66/106). The consistency rate of Gleason scores in both specimens was 69% (70/106). High positive core rate detected in biopsy was associated with more extracapsular invasion and perineural invasion (PNI) in radical prostatectomy specimens (p<0.001, p=0.010, respectively). The high mean tumor percentage detected in biopsy was associated with high extracapsular extension, PNI, and high surgical margin positivity in radical prostatectomy specimens (p<0.001, p=0.004, p=0.021, respectively). High Gleason score detected in biopsy was associated with higher tumor percentage, higher extracapsular extension, and more PNI in radical prostatectomy specimens (r=0.302, p=0.002, r=0.316, p=0.001, r=0.238, p=0.014, respectively). CONCLUSIONS: The pathological data of TRUS-Bx will determine the treatment to be applied, but it should be kept in mind that although its place in prostate cancer is undisputed, it may not be completely correlated with radical prostatectomy pathology. Additional tools are needed to bring this correlation to higher levels. However, it should be taken into account that the high number of cancer detected cores and the high mean tumor percentage in TRUS-Bx, may lead to a more advanced tumor risk in radical prostatectomy specimens.

Anahtar Kelimeler: