Cytomegalovirus (CMV) pneumonia is a rare opportunistic infection in the progression of human immunodeficiency virus (HIV) infection. Also, COVID-19 has been named a pandemic since the beginning of 2020. During this period, physicians were exposed to many COVID-19 cases, and it was challenged to consider different diagnoses in patients who applied to the emergency room with lung complaints and bilateral pneumonia. Here we reported a 30-year-old man diagnosed with HIV- associated opportunistic CMV pneumonia mimicking COVID-19. The diagnosis of CMV pneumonia was obtained through consistent clinical, radiological, microbiological and cytologic examinations. The patient made a complete clinical recovery after being initialized on anti-CMV treatment.
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