Introduction: Depression and anxiety disorders which are counted as common mental disorders effect 2-6% of general population. In the treatment of common mental disorders, anemia, thyroid dysfunctions, general medical issues and central nervous system diseases must be kept in minds. In this paper, medical files of patients who had been hospitalized in Ankara University Faculty of Medicine, Psychosomatic Unite of Mental Health and Disorders Department cause of treatment resistance or insufficent treatment response were examinede retrospectively. Purpose of this study is identifying and sociodemographic and clinical features and exhibiting relationship between these in treatment resistant patients. Method: Patients that applied to Ankara University Faculty of Medicine Psychosomatic Unite between September 2017-June 2018 and were diagnosed as depression, anxiety disorders, obsessive-compulsive disorder or somatoform disorders were selected(n=60). Patients were hospitalized in twelve personed groups for 2 months and were treated with group and individual psychotherapies and psychotropic drugs. Sociodemographic data, clinical findings detected from medical files, serum vitamine B12 and TSH levels and cranial MRI reports were used for analysis. SPSS 21.0 was used and p<0,05 was accepted for significancy. Results: Depressive symptoms were the most observed symptoms. There were significant relationship with sexual abuse history and female sex, and physical abuse history and depressive symptoms (resptectively p=0,025; 0,021). And also there was significant relationship between anxiety symptoms and mental disorder in relatives(p=0,012). There was no relationship rest of clinical and sociodemographic data. There was no relationship between laboratuary data and the other variables but total symptom number was significantly related frontal white matter hiperintensity (p=0,022). Conclusion: In the end patient with mental disorder must be evaluated not only mental aspect but also biological and social aspects. The treatment of patients can be carried holistically if only that kind of evaluation is made.
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