Abstract:

Objective: The data reflecting adverse effects seen during the treatment of nephrotic syndrome NS in Turkey are limited. In this study, we aimed to evaluate the side effects of treatment of NS patients observed at our clinic.Material and Method: We retrospectively reviewed the data of 206 patients with NS 126 male; 80 female followed up at the Pediatric Nephrology outpatient clinic of the Istanbul University Istanbul Medical Faculty between 1986-2010.Results: Mean age of 206 126 male, 80 female patients at the time of admission was 3.8±2.8 years range: 0.2-13.8 . During follow-up, 171 patients 83% experienced at least one side effect due to any of the drugs. The most frequent side effects of steroid treatment in order of decreasing frequency were cushingoid appearance 52% , hypertension 23.4% , growth retardation 17% , cataract 6.8% and osteoporosis 6.8% . Total duration of steroid use and steriod dose were higher in the patients who suffered from growth retardation, osteoporosis, cataract, hypertension than in those who did not suffer these side effects p

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