Abstract:

The presence of anti-nuclear antibodies (ANA) is one of the important indicators of systemic joint tissue diseases. It is known that the anti-DFS70 autoanticor is also seen in healthy individuals and its connection to the disease has not yet been determined. Our study aimed at investigating the relationship between the clinical proximity, diagnosis and inflammatory parameters of patients diagnosed with the indirect immune fluoresan-ANA (IIF-ANA) and immunoblot method with anti-DFS70 antibody positive [C-reactive protein (CRP), erythrosite sedimentation rate (ESR) and the Romatoid Factor (RF)]. Method: The study included 412 (91.5) women in the age range of 4-90 years, 38 (8.5) men, 450 patients. The clinical diagnoses of patients and inflammatory parameters were evaluated retrospectively. The findings were: Acne, pain (126/136) and eruption, breathing difficulty, swelling (10/136). In 81 patients with pain approximation (64.3%), inflammation was uncoverable, while in 45 (35.7%), it was detected and statistically meaningful (p=0.001). Inflammation was found negative in 106 patients with a systemic retention of joint tissue (67.9 percent), positive in 50 (p<0.001) and negative in 19 patients with urethra (95) and positive in 1 (p<0.001) (p<0.001). It was found that 10 of the 60 patients who received the exact diagnosis received a systemic retention of joint tissue, 10 were urethral, and 40 received different diagnoses. Result: Our study found that DFS70 positivity was higher in women and that this father could be accompanied by many diseases. Our study also suggests that when the cause of pain approach is eliminated, inflammatory parameters may be DFS70 antibodies and there may be a relationship between the urethral and the DFS70 autoanticors.

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