Özet:

Background: Development of minimally invasive laparoscopic cholecystectomy reduced surgical site infection (SSI), length of hospital stay, healthcare costs, and postoperative pain. To prevent any complication, intravenous antibiotics are preferred by most surgeons as prophylaxis. Moreover, controversy still exists regarding the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy. Therefore, we performed to assess the antibiotic utilization in patients undergoing cholecystectomy in a tertiary care hospital. Materials & Methods: A prospective analytic study done on 100 patients those undergoing planned Cholecystectomy operation (open or laparoscopic method) in the department of general surgery at Darbhanga Medical College, Bihar, India during one year period. On post operative period, the patient bed side tickets were used to collect the data regarding antibiotics drugs prescribed with their dosage and route of administration. The patient was followed till discharge for any addition of drugs and on discharge the discharge date was noted which signified the length of drug used during the post operative period. Results: Majority of case were seen in 41-50 years of age groups (55%) and female preponderance (70%) in our study. The Antibiotic usage in open Cholecystectomy shows that mostly metronidazole (47%) and Cefoperazone – Sulbactam (25%) are used post operatively. The overall average duration of hospital stay was 6-7 days. Maximum number of patients with 6 days duration received metronidazole in open Cholecystectomy procedure. In Laparoscopic Cholecystectomy, the average post operative stay period is around 3-4 days. Cefoperazone sulbactam and Metronidazole combination has been given in these cases mainly. Conclusion: Antibiotic prophylaxis is safe and effective in reducing surgical site infections and global infections during hospitalization or after discharge, and postoperative length of hospital stay in low-risk patients undergoing elective laparoscopic cholecystectomy.

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