Abstract:

Objective: Acute coronary syndromes (ACS) are still the main cause of mortality in the world. Scoring systems are important for risk evaluation in ACS. Angiographic The Synergy between Percutaneous Coronary Intervention (SYNTAX) score is universal. For cardiac pump function, left ventricular (LV) longitudinal shortening has a major role. It can be assessed by some echocardiographic parameters. Mitral annular plane systolic excursion (MAPSE) is well defined for the LV longitudinal function evaluation and clues with LV systolic function. In this study, we aimed to research the relationship between SYNTAX score and MAPSE in Non-ST elevation myocardial infarction (NSTEMI) patients. Methods: 138 consecutive patients who underwent coronary angiography after diagnosis of NSTEMI were included. Transthoracic echocardiography was performed to all patients by an experienced physician who was uninformed patient’s data. Coronary angiography via the femoral approach was performed for all patients within 48 hours. ≥ 50% coronary lesion stenosis in vessels ≥ 1.5 mm was scored separately and SYNTAX scores were obtained. Results: The median age was 64.5 (54.0-70.8) years and 80.4% were male. Hypertension was the most common risk factor (72.5%). Left anterior descending artery (LAD) stenosis was the most common artery stenosis (58.7%). The mean MAPSE was 14.0 (13.0-15.8) and the mean SYNTAX score was 10.0 (7.0-14). Correlation of our outcome variable SYNTAX score between physiological and clinical variables of age, troponin and LVEF were calculated. No significant p value was detected. The relationship between SYNTAX Score and categorical variables such as gender, hypertension, diabetes mellitus, hyperlipidemia, left main coronary artery (LMCA), LAD, right coronary artery (RCA), circumflex artery (CX), peripheral arterial disease (PAD) was evaluated. None of the variables included in the regression model were associated with the SYNTAX score Conclusion: In this study, we have investigated the relationship between MAPSE and SS in NSTEMI patients. No significant correlation was found between MAPSE and SS.

Keywords: