Selective serotonin reuptake inhibitors can lead to increased prolactin levels and galactorrhea. Herein, we reported a 40-year-old female patient who developed galactorrhea and hyperprolactinemia two weeks after initiation of fluoxetine 20 mg/day. Galactorrhea was discontinued after the fifth week of fluoxetine withdrawal and prolactin levels reached normal limits. The patient's depressive symptoms disappeared with citalopram 40 mg/day and no similar side effects were observed during follow-up. Clinicians should be aware of the hyperprolactinemia and galactorrhea adverse effects of fluoxetine.
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