Özet:

Objective: We wanted to evaluate the dose intensity and the rate of opioid use in patients hospitalized with a diagnosis of cancer at Medical Oncology Department.Cancer pain, opioid therapy, low-dose opioid, high-dose opioid Patients and Methods: June to December 2014, data were retropectively analiysed from 173 patients in 490 advanced cancer patients who were admitted to our clinic and received opioid treatment. Types of opioid use divided as weak (equal  to ≤100 mg/day and strong (equal to >100 mg/day morphine), and the opioid dose intensity were examined. Results: A total of 173 patients, 114 (66.3%) were male and 58 (33.7%) were female, mean age of 59.9±4.12 were found. 141 (81.5%) patients had metastases, 32 (18.5%) patients had no metastases. According to type of cancer, 37 patients were classified (21.4%) lung, 34 (19.7%) of the stomach, 22 patients (12.7%), breast, and 17 (9.8%), leukemia, lymphoma, 16 (9.2%), colon and 16 (9.2%) of the prostate, 11 patients (6.4%), the rectum, and 10 (5.8%), pancreatic cancer, and 10 patients (5.8%) present in other cancers. There were no statistically differences found among opioid side effects according to opioid dosage (P > 0.05). Conclusion: Regardless of the type of cancer, high doses of opioid are required in at least one of the three opioid-utilizing patients. Since high dose opioid use does not bring with it a higher risk of side effects, the opioid should be used in an effective and very high dose of opioid when it is needed for palliation of pain in cancer patients.  

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