Özet:

Purpose: Evaluation of the factors affecting success in patients with micro-TESE (microcirurgical testicular sperm extraction) due to nonobstructive azoospermia (NOA). Tools and Methods: The age, infertility periods, operations, serum follicle-stimulating hormone (FSH), total testosterone levels, testicular dimensions, testicular histopathological findings and the effects of these parameters on the success of obtaining sperm in the micro-TESE were evaluated retrospective. Results: 37 (45.7%) of 81 patients found TESE positive; 44 (54.3%) found TESE negative. There were no significant differences in sperm positivity between patients divided into 2 groups (22-34 and 35-60) according to their age. and p = 0. of 778). The infertility period is between 1-21 years. In eight patients (9.8%) there was a genetic anomaly (6 Klinefelter syndrome and 2 AZFC divisions), and TESE positive was significantly low in Klinefelter patients (P=0.029). According to the hormone profile, the average FSH in micro-TESE-positive patients was significantly low (P=0.04), while there was no statistically significant difference in total testosterone levels (P=0.109). While the effect of testicular dimensions on sperm finding was not determined (P=0.3), the probability of sperm finding was lower than hypospermatogenesis in those diagnosed with maturity arresti in histopathology, Sertoli cell only and fibrosis (respectively; 35%, 26% and 14%). The result is that there is a statistically meaningful relationship between the genetic disease accompanied by the success of obtaining sperm in micro-TESE, the serum FSH values and testicular histopathology; the patient’s age, infertility period, testicular dimensions, the relationship with the serum testosterone values and the effect of the same age on pregnancies that will be formed with the obtaining sperm are not clear.

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