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Congenital syphilis is a severe disease that arises from the vertical transmission of Treponema pallidum. Clinical findings are related to the pregnancy stage, fetal gestational week, maternal treatment and fetal immunologic response. Prematurity, low birth weight, nonimmune hydrops fetalis, necrotizing enterecolitis, hepatomegaly, skin eruptions, thrombocytopenia, hemolytic anemia and fever can be detected in the symptomatic newborn. Postnatal respiratory insufficiency, hepatomegaly, anemia and thrombocytopenia were detected in a baby who was born at the 29th week of gestation, weighing 1.160 g and followed due to intestinal hyperechogenicity from the second trimester. Her and her mother’s Venereal Disease Research Laboratory titers were positive, confirming test Treponema pallidum hemagglutination was reactive. After penicillin was administered for 10 days, anemia, and thrombocytopenia were regressed. In the 15th day of life, findings of perforated necrotising enterocolitis (NEC) suddenly appeared. The operation was performed due to NEC for three times but nonresponsive laboratory and clinical findings and died in the 54th day of life. We assumed that syphilis is the cause of both bowel hyperechogenicity and necrotising enterocolitis.
Congenital syphilis is a serious disease caused by the vertical transition of treponema pallidum. Clinical findings occur according to the stage of pregnancy, the gestational week of the fetus, maternal treatment and the immune response of the fetus. In symptomatic newborns; early birth, low birth weight, nonimmune hydrops fetalis, necrotizan enterokolite (NEK), hepatomegaly, skin outbreaks, trombocytopenia, hemolithic anemia and fever can be detected. From the second trimester, a girl born at 1,160 g in the 29th week of pregnancy, followed by the cause of cervical hyperecogenicity, was diagnosed with postnatal respiratory failure, hepatomegaly, anemia and trombocytopenia. In the baby and mother, the Venereal Disease Research Laboratory titrals were positive, confirmation test Treponema pallidum hemaglutination examination reactive. After 10 days of penicillin administration, anemia and trombocytopenia improved. In the postnatal 15th day there was sudden development of perfore necrotic NEK. Three times the patient was missing in the 54th day of his lifetime, despite the clinical and laboratory findings. We believe that congenital syphilis is the cause of both prenatal intestinal hyperecogenicity and NEK. (SETB-2018-08-113)
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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