Özet:

The present study was aimed to determine changes in the levels of oxidative stress markers such as Malondialdehyde (MDA) and the antioxidant levels such as Glutathione (GSH) and Superoxide Dismutase (SOD) in different organs such as liver, kidney, muscle, and serum samples of Carassius gibelio exposure to low (1 µgL-1), middle (1.5 µgL-1) and high (2 µgL-1) doses Cypermethrin for 96 h. The results showed significant increase in MDA of the liver and muscle tissues (p<0.001 level in all groups) with serum samples (p<0.01, p<0.001, p<0.001 respectively). SOD levels was determined that the significant decrease in liver (p<0.05, p<0.01, p<0.001 respectively), muscle tissues (p<0.001 level in medium and high doses) and serum samples (p<0.01 level in high dose). Moreover GSH levels was detected that significant decrease in the muscle (p<0.001, p<0.001, p<0.05 respectively) and serum samples (p<0.01 level in high doses). We did not observe a significant difference of the oxidant and antioxidants levels in the kidney tissue (p>0.05). The uncontrolled, insensible and unnecessary usage of pesticides such as Cypermethrin can be use serious hazard to the environment and public health. The result of the study showed that the very important corruption balance between oxidants and antioxidants depend on Cypermethrin exposured even in short period.

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