Özet:

The aim of this study was to investigate the correlation between TVUS measurement of endometrial thickness and endometrial biopsy results in peri- and postmenopausal women with abnormal uterine bleeding. The study included 27 perimenopausal and 26 postmenopausal women. Endometrial thickness was measured with TVUS. The patients were divided into 4 groups according to the measurement findings: such as 0-5, 6-10, 11-15 and 16-20 mm. Dilatation and curettage was performed in all cases under local anaesthesia. The values of endometrial thickness are compared with endometrial histopathology. Mann Whitney U test was used for statistical analysis. When the cut-off value of endometrial thickness in the perimenopausal period was 10 mm, the sensitivity, specificity, positive and negative predictive values in prediction of endometrial pathology were 85.7 %, 60 %, 42.35 %, 92.35 % respectively. In the postmenopausal period, these values corresponded 92.3 %, 71.4 %, 85.7 %, 83.3 % respectively with the same cut-off value. The mean values of endometrial thickness measured by TVUS for endometrial hyperplasia without atypia, endometrial polyp and endometrial carcinoma were found to be 14.68±32 mm, 10.95±2.61 mm, 16.45±2.47 mm respectively. Given that the sensitivity and specificity for measuring the endometrial thickness by TVUS in the postmenopausal period are superior to those in the perimenopausal period. It seems reasonable that vaginal ultrasonographic assessment of the endometrium should be primary method for excluding any endometrial abnormality in a woman with postmenopausal bleeding.

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