Views
29
Downloands
3
Primer santral sinir sistemi vasküliti (PSSSV), sistemik vaskülit belirtisi olmadan beyin ve omurilikteki damarlarının nadir bir inflamatuar hastalığıdır. Tanı zorluğu nedeniyle tam insidansını belirlemek zordur. Klinik geniş nörodefisitler içerebildiği gibi subakut-kronik seyirlidir. Kesin tanı için önerilen biyopsi veya serebral anjiografinin beklendiği kadar yüksek özgüllüğü yoktur. Prodromal bir kliniğin bulunması, nörodefisit varlığı, sistemik bulguların ekartasyonu, MRG’de atipik lezyonların varlığı, anormal BOS analizi ile de olası PSSSV tanısına ulaşılabilir. Tedavide steroid ve siklofosfamid gibi immunsüpresif ajanlar kullanılmaktadır. Bu yazıda anormal BOS bulgularının olduğu ve MR spectroskopiden faydalanılarak olası PSSSV tanısı alan olgu sunulmuştur.
Primary central nervous system vasculitis (PSSSV) is a rare inflammatory disease of the brain and spinal vessels without any symptoms of systemic vasculitis. It is difficult to determine the complete incidence due to the diagnosis difficulty. The clinic is subacute-chronic as it can contain broad neurodepicates. The recommended biopsy or brain angiography for a precise diagnosis has no higher specificity than expected. The presence of a prodromal clinic, the presence of neurodepinitis, the extraction of systemic findings, the presence of atypical lesions in MRG, an abnormal BOS analysis can also be achieved to the possible diagnosis of PSSSV. In the treatment, immunosuppressants such as steroids and cyclophosphamide are used. This article presents the fact that there are abnormal BOS findings and possibly diagnosed with PSSSV using the MR spectroscope.
Primary central nervous system vasculitis (PCNSV) is a rare inflammatory disease of the vessels of the brain and spinal cord without signs of systemic vasculitis. Due to the difficulty of diagnosis, it is difficult to determine the exact incidence. Clinical findings may include a wide variety of neurodeficides and are subacute-chronic. The biopsy or cerebral angiography recommended for definitive diagnosis does not have as high specificity as expected. The presence of a prodromal clinic, the presence of neurodeficitis, the elimination of systemic findings, the presence of atypical lesions on MRI, and abnormal CSF analysis can also lead to a diagnosis of PSSSV. Immunosuppressive agents such as steroids and cyclophosphamide are used in the treatment. In this article, we present a case with abnormal CSF findings and a diagnosis of possible PSSSV using MR spectroscopy.
Field : Sağlık Bilimleri
Journal Type : Uluslararası
Article Detail 
Similar Articles
Download PDF
Journal Information
Listen Paper
Cite
Print This Page
Share
Mendeley
