Özet:

Abstract Objective: In our study, we aimed to investigate some laboratory parameters in patients diagnosed with alcohol / substance use disorder (ASUD) by comparing with a healthy control group. Materials and Methods: Patients diagnosed with opioid, methamphetamine, alcohol, and multiple substance use disorders according to DSM-5 criteria who were hospitalized in Gaziantep State Hospital Alcohol and Substance Addiction Treatment Center (AMATEM) service on December 25 were included in this study. Study group consisted of 612 patients while the control group consisted of 117 healthy subjects. Laboratory parameters of the participants were analysed retrospectively from the hospital data. Results: Among the patients included in our study, 23 patients were female, while 706 were male. Mean age was 40.91 ± 29.58 years. Blood electrolyte levels of sodium were higher in patients with opioid, methamphetamine, and multiple substance use disorders compared to healthy controls and patients with alcohol use disorder (F = 14.651, P <0.001). In patients with opioid, methamphetamine, and multiple substance use disorder, potassium levels were higher than healthy controls and patients with alcohol use disorder (F = 16.938; P <0.001). In patients with alcohol use disorder, liver enzymes were found to be higher than other groups, while urea value was found to be low. Discussion / Conclusion: Our results showed that liver enzymes, kidney functions, electrolyte levels, and blood lipid profiles of patients with alcohol / substance use disorder were affected. Based on the results we obtained, it should be taken into consideration in treatment schedules that patients with alcohol / substance use disorder may have single or multiple organ damage and/or structural and functional effects.

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