Autoimmune cholangiopathy or IgG4-related sclerosan cholangitis is an immune- mediated type of cholangitis. Autoimmune pancreatitis is frequently associated with this condition. However, in a minority of patients, autoimmune cholangiopathy exist alone. A 69- year-old female patient was admitted to our hospital with fatigue, pruritus, and jaundice. There were multiple strictures and dilations in the intrahepatic biliary tree with stricture in the distal part of the common bile duct. To exclude other causes of sclerosan cholangitis, IgG4 was studied. The IgG4 titer was 1200 mg/dl; therefore, the diagnosis was autoimmune cholangiopathy. Autoimmune cholangiopathy must be investigated in patients with biliary strictures in either the intrahepatic or extrahepatic bile ducts. IgG4 can be used to screen for autoimmune cholangitis. Diagnosis and treatment of this condition prevents patients from cirrhosis and unnecessary surgery.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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