Abstract:

INTRODUCTION: To evaluate indications and histopathological diagnoses of endometrial samplings in our clinic. METHODS: Seven hundred and fourty four subjects who required endometrial biopsy to be taken for any indication other than pregnancy between January 2013 and January 2014 were included in the study. Data collected retrospectively from Dumlupinar University Evliya Celebi Training and Research Hospital obstetrics and gynecology clinic database and pathology clinic. Statistical analysis of data was performed using SPSS for Windows 13 package programme. RESULTS: Mean age of the subjects was 43.6 ± 8.3. Indications of endometrial sampling were menorrhagia/ menometrorrhagia (87%), myoma uteri (1.6%), postmenopausal bleeding (9.5%), cervical polyp (1.9%). Histopathologic diagnoses were as follows: secretory/proliferative endometrium in 72.8%, atrophic endometrium in 3.5%, simple atypical endometrial hyperplasia in 0.7%, simple typical endometrial hyperplasia in 7.9%, complex atypical endometrial hyperplasia in 0.3%, complex typical endometrial hyperplasia in 0.3%, atrophic endometrium in 3.5%, endometrium cancer in 0.8%, and endometrial polyp in 9.5%. Insufficient sampling material was reported in 0.9%. Endometrium cancer was detected in 5.6% of postmenopausal group. DISCUSSION AND CONCLUSION: The most common endometrial sampling indication was menorrhagia/menometrorrhagia, while endometrium cancer was detected most commonly in patients with postmenopausal bleeding. Our results emphasize that endometrial sampling is warranted especially in peri/postmenopausal women with abnormal uterine bleeding. Endometrial evaluation is needed in patients with cervical polyp.

Keywords: